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In one embodiment, the method comprises introducing into an organism a target gene of interest which is under the control of at least one tet operator and an expressible nucleotide sequence encoding a revTetR, and contacting the organism with a concentration of tetracycline or tetracycline analog sufficient to alter the level of transcription of the target gene! Most dopamine-producing neurons are located in areas near the brainstem!

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In an embodiment, zovirax cream price philippines the 7,9-substituted tetracycline compound is 7,9-substituted tetracycline (eg, wherein R 4 is NR 4 R 4"; R 4' and R 4" are methyl, R s is hydrogen and X is CR 6R 6', wherein R 6 is methyl and R 6 is hydroxy); 7,9-substituted doxycycline (eg, wherein R is NR >4 4'r R4 4" ; R 4' and R 4" are methyl, R 5 is hydroxyl and X is CR > 6°τR)6°' , wherein R D is methyl and R 6 is hydrogen); or 7, 9- substituted sancycline (wherein R 4 is NR 4 R 4 ; R 4 and R 4 are methyl; R 5 is hydrogen and X is CR 6R 6 wherein R 6 and R 6 are hydrogen atoms.

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